Session VI: Translating Discoveries

RSwitch-enabled Gene Therapy to Fine Tune Frataxin Expression for the Treatment of Friedrich’s Ataxia

June 27, 2025 | 4:15 – 4:25 PM | ASC2.2102

Jon Dempersmier

Rgenta Therapeutics

Jon Dempersmier, Rgenta Therapeutics
Detail-oriented cell biologist/ biochemist with 15 years experience in an academic setting. Well versed in characterization of transcriptional and translational regulation in a variety of systems including metabolic tissues and cancer using in vitro assays, cell culture, and animal models with a track record of successful publications. Jon's recent work has included assay development and testing of novel compounds (PROTACs, stapled peptides, and small molecules) targeting cancer vulnerabilities in cell-based assay systems as well as protein engineering of novel regulatory domains.