Dr. Daniel Dominguez is an Assistant Professor in the Department of Pharmacology at the University of North Carolina at Chapel Hill. He earned his PhD at UNC Chapel Hill and completed postdoctoral training with Dr. Chris Burge at MIT.

His research focuses on RNA biology and gene regulation, particularly in the context of cancer and neurodegenerative disease. The Dominguez Lab investigates the molecular mechanisms of RNA-protein interactions and their regulatory consequences, using a multidisciplinary approach that combines computational biology, molecular biology, high-throughput biochemical assays, and animal models.

Previous work has included developing nuanced models of RNA-binding protein (RBP) specificity, examining the functional impact of RBP mutations, exploring the evolution of RNA-protein interactions, and uncovering mechanisms of alternative splicing in cancer and cell cycle regulation. The lab’s research is supported by the National Cancer Institute (NCI), the National Institute of General Medical Sciences (NIGMS), and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).