Xiaowei Zhuang is an investigator of Howard Hughes Medical Institute and the David B. Arnold Professor of Science at Harvard University. She pioneered the development of super-resolution imaging and genome-scale imaging methods. She invented STORM, a super-resolution imaging method that overcome the diffraction limit, and discovered novel molecular structures in cells using STORM. She invented a single-cell transcriptome and genome imaging method, MERFISH, which enabled spatial genomics. Using MERFISH, she made discoveries in the areas ranging from the cellular organization and functions in the brain and genetic regulators of liver functions to the 3D genome organization and gen regulation in cells.

Zhuang received her Ph.D. degree in physics under the supervision of Prof. Y. R. Shen from University of California at Berkeley, and her postdoctoral training in biophysics in the lab of Prof. Steven Chu at Stanford University. She received honorary doctorate degrees from the Stockholm University, the Delft University of Technology, and the Icahn School of Medicine at Mount Sinai. She is a member of the National Academy of Sciences, National Academy of Medicine, and the American Academy of Arts and Sciences, a fellow of the National Academy of Inventors, a member of the American Philosophical Society, and a foreign associate of the Chinese Academy of Sciences and the European Molecular Biology Organization. Her awards include the National Inventors Hall of Fame, the

Dreyfus Prize in Chemical Sciences, the Heinrich Wieland Prize, the Breakthrough Prize in Life Sciences, the Heineken Prize for Biochemistry and Biophysics, the Lurie Prize in Biomedical Sciences, the Vilcek Prize in Biomedical Science, the Pearl Meister Greengard Prize, the National Academy of Sciences Award for Scientific Discovery, the Raymond and Beverly Sackler International Prize in Biophysics, the Max Delbruck Prize in Biological Physics, the MacArthur Fellowship, etc.